SHANGHAI OCEANHOOD OPTO-ELECTRONICS TECH CO., LTD.

手机官网

|

简体中文

|

English
Solutions
Application Area

Location: OCEANHOOD Home > Solutions

Quinolone antibiotics exceed the standard, take it seriously!

Launch:2022-06-28    

   image.png

Fish often as a delicacy appears on the table of people in various countries, because its meat is tender, rich in protein, vitamins and other nutrients. But it also often as an integral part of a healthy diet. And what is the substance of "Enrofloxacin" detected in the fish meat; and why does it not meet the national food safety regulations because it exceeds the standard?

Introduction to quinolone antibiotics

Enrofloxacin is a class of the same as the addition of a third-generation antibiotic in the class of quinolones. The antibacterial effect of such drugs is generally good, and it has the advantages of a wide range of antibacterial and strong bactericidal ability. It is an effective drug for the prevention and control of bacterial diseases in aquatic animals.

image.png

What harm will exceed the standard cause to the human body?

After human consumption of animal tissues, long-term use of quinolone residue food can cause human diseases to be seriously resistant to the drug. This may cause respiratory infections, genetic mutations, carcinogenicity, and over time, affect the treatment of human diseases.

Therefore, ciprofloxacin in antibacterial drugs has been banned. Enrofloxacin residue has been used as a major factor restricting eel exports to Japan. The attention and influence of antibiotic content indicators are constantly expanding.

So how should we test whether the quinolone antibiotic in animal sources meets the national standard?

Different from the current colloidal gold and Elisa methods, such as the Raman spectroscopic rapid detection scheme developed by Oceanhood, it provides an efficient method for the detection of quinolone antibiotics in animal-derived foods.


image.png

Testing for quinolone antibiotics in foods of animal origi 

01 Experimental materials:

Salmon, blackfish, grass carp, pork.

02 Experimental methods

1)  Enhanced tests were performed on the specimen to obtain the characteristic peaks of dafloxacin and difloxacin.

Sample

Feature peakscm-1

Dafloxacin

554740767

Difloxacin

5477447818148601156

2 Animal-derived samples are pre-processed to extract the antibiotics from them.

3The sample is marked to begin enhanced testing. 

image.png

Fig. 1 Test results of 0.1 ppm dafloxacin in pork


image.png

Fig. 2 Test results of 0.1 ppm difloxacin andfloxacin in pork


matrix

concentrationmg/kg

Test   results

Label

Dafloxacin/difloxacin

salmon

0.01

+

salmon

0

snakehead

0.1

+

Grass carp

pork

Note: + indicates checked out, — indicates no checkout

03 Experimental results

0.1 mg/kg of animal source samples can be detected, and the test time is only 10-15 min (including the whole process of pretreatment and detection)

04 Conclusion

Through the Raman spectroscopy equipment (pre-treatment integrated machine; detection equipment is: SEED3000) and SERS rapid detection method independently developed by Oceanhood, it provides an efficient analysis method for the detection of satoxane drugs in animal-derived foods. This allows the relevant departments to take precautions, quickly screen out unqualified and substandard food sources, and no longer fear the harm caused by quinolone antibiotics.

image.png【17】SEED3000.jpg

image.png